PHD3 Acts as Tumor Suppressor in Mouse Osteosarcoma and Influences Tumor Vascularization via PDGF-C Signaling

Cancer cell proliferation and insufficient blood supply can lead to the development of hypoxic areas in the tumor tissue. The adaptation to the hypoxic environment is mediated by a transcriptional complex called hypoxia-inducible factor (HIF). HIF protein levels are tightly controlled by oxygen-depe...

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Detalles Bibliográficos
Autores principales: Egners, Antje, Rezaei, Maryam, Kuzmanov, Aleksandar, Poitz, David M., Streichert, Doreen, Müller-Reichert, Thomas, Wielockx, Ben, Breier, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316346/
https://www.ncbi.nlm.nih.gov/pubmed/30563292
http://dx.doi.org/10.3390/cancers10120496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316346/
https://www.ncbi.nlm.nih.gov/pubmed/30563292
http://dx.doi.org/10.3390/cancers10120496

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