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ISG15 Promotes ERK1 ISGylation, CD8+ T Cell Activation and Suppresses Ovarian Cancer Progression

Increased number of tumor-infiltrating CD8+ lymphocytes is associated with improved survival in patients with advanced stage high grade serous ovarian cancer (HGSOC) but the underlying molecular mechanism has not been thoroughly explored. Using transcriptome profiling of microdissected HGSOC tissue...

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Detalles Bibliográficos
Autores principales:	Yeung, Tsz-Lun, Tsai, Ching Chou, Leung, Cecilia S., Au Yeung, Chi-Lam, Thompson, Melissa S., Lu, Karen H., Freedman, Ralph S., Birrer, Michael J., Wong, Kwong-Kwok, Mok, Samuel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316352/ https://www.ncbi.nlm.nih.gov/pubmed/30469497 http://dx.doi.org/10.3390/cancers10120464

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