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MicroRNA-Attenuated Virus Vaccines

Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of host-derived microRNAs (miRNAs) to attenuate...

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Detalles Bibliográficos
Autores principales: Fay, Elizabeth J., Langlois, Ryan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316615/
https://www.ncbi.nlm.nih.gov/pubmed/30279330
http://dx.doi.org/10.3390/ncrna4040025

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