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MicroRNA-Attenuated Virus Vaccines
Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of host-derived microRNAs (miRNAs) to attenuate...
Autores principales: | Fay, Elizabeth J., Langlois, Ryan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316615/ https://www.ncbi.nlm.nih.gov/pubmed/30279330 http://dx.doi.org/10.3390/ncrna4040025 |
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