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A Standardized Collagen-Based Scaffold Improves Human Hepatocyte Shipment and Allows Metabolic Studies over 10 Days

Due to pronounced species differences, hepatotoxicity of new drugs often cannot be detected in animal studies. Alternatively, human hepatocytes could be used, but there are some limitations. The cells are not always available on demand or in sufficient amounts, so far there has been only limited suc...

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Detalles Bibliográficos
Autores principales: Ruoß, Marc, Häussling, Victor, Schügner, Frank, Olde Damink, Leon H. H., Lee, Serene M. L., Ge, Liming, Ehnert, Sabrina, Nussler, Andreas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316810/
https://www.ncbi.nlm.nih.gov/pubmed/30332824
http://dx.doi.org/10.3390/bioengineering5040086