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A Standardized Collagen-Based Scaffold Improves Human Hepatocyte Shipment and Allows Metabolic Studies over 10 Days
Due to pronounced species differences, hepatotoxicity of new drugs often cannot be detected in animal studies. Alternatively, human hepatocytes could be used, but there are some limitations. The cells are not always available on demand or in sufficient amounts, so far there has been only limited suc...
Autores principales: | Ruoß, Marc, Häussling, Victor, Schügner, Frank, Olde Damink, Leon H. H., Lee, Serene M. L., Ge, Liming, Ehnert, Sabrina, Nussler, Andreas K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316810/ https://www.ncbi.nlm.nih.gov/pubmed/30332824 http://dx.doi.org/10.3390/bioengineering5040086 |
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