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Structural Basis of DNMT1 and DNMT3A-Mediated DNA Methylation

DNA methylation, one of the major epigenetic mechanisms, plays critical roles in regulating gene expression, genomic stability and cell lineage commitment. The establishment and maintenance of DNA methylation in mammals is achieved by two groups of DNA methyltransferases (DNMTs): DNMT3A and DNMT3B,...

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Detalles Bibliográficos
Autores principales:	Ren, Wendan, Gao, Linfeng, Song, Jikui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316889/ https://www.ncbi.nlm.nih.gov/pubmed/30544982 http://dx.doi.org/10.3390/genes9120620

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