Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl(2) infused gelatine slurry to form filaments, which are consequently...

Descripción completa

Detalles Bibliográficos
Autores principales: Štumberger, Gabriela, Vihar, Boštjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316925/
https://www.ncbi.nlm.nih.gov/pubmed/30545119
http://dx.doi.org/10.3390/ma11122529
Descripción
Sumario:We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl(2) infused gelatine slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering.

Ejemplares similares