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Implications of Na(+)/I(-) Symporter Transport to the Plasma Membrane for Thyroid Hormonogenesis and Radioiodide Therapy
Iodine is a crucial component of thyroid hormones; therefore, a key requirement for thyroid hormone biosynthesis is that iodide (I(−)) be actively accumulated in the thyroid follicular cell. The ability of the thyroid epithelia to concentrate I(−) is ultimately dependent on functional Na(+)/ I(−) sy...
Autores principales: | Martín, Mariano, Geysels, Romina Celeste, Peyret, Victoria, Bernal Barquero, Carlos Eduardo, Masini-Repiso, Ana María, Nicola, Juan Pablo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316985/ https://www.ncbi.nlm.nih.gov/pubmed/30620007 http://dx.doi.org/10.1210/js.2018-00100 |
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