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Implications of Na(+)/I(-) Symporter Transport to the Plasma Membrane for Thyroid Hormonogenesis and Radioiodide Therapy

Iodine is a crucial component of thyroid hormones; therefore, a key requirement for thyroid hormone biosynthesis is that iodide (I(−)) be actively accumulated in the thyroid follicular cell. The ability of the thyroid epithelia to concentrate I(−) is ultimately dependent on functional Na(+)/ I(−) sy...

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Detalles Bibliográficos
Autores principales: Martín, Mariano, Geysels, Romina Celeste, Peyret, Victoria, Bernal Barquero, Carlos Eduardo, Masini-Repiso, Ana María, Nicola, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316985/
https://www.ncbi.nlm.nih.gov/pubmed/30620007
http://dx.doi.org/10.1210/js.2018-00100

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