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Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters
A method for obtaining highly porous materials in the form of film, based on the butyric-acetic chitin co-polyesters, containing 90% of butyryl and 10% of acetyl groups, was developed. The highly porous films, with thickness up to 0.11 mm, were obtained by two methods: (a) pouring 5% BAC 90/10 solut...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317001/ https://www.ncbi.nlm.nih.gov/pubmed/30477125 http://dx.doi.org/10.3390/ma11122359 |
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author | Draczynski, Zbigniew Kolesinska, Beata Latanska, Ilona Sujka, Witold |
author_facet | Draczynski, Zbigniew Kolesinska, Beata Latanska, Ilona Sujka, Witold |
author_sort | Draczynski, Zbigniew |
collection | PubMed |
description | A method for obtaining highly porous materials in the form of film, based on the butyric-acetic chitin co-polyesters, containing 90% of butyryl and 10% of acetyl groups, was developed. The highly porous films, with thickness up to 0.11 mm, were obtained by two methods: (a) pouring 5% BAC 90/10 solution in ethanol on the layer of solid salts (porophor agent) which after solidification was eluted with water; (b) application of the suspension of porophor agent in BAC 90/10 solution in the solvent mixture with density similar to bulk porophor agent. In the final stage, the materials were obtained with porosity up to 95–99% and tensile strength 5 cN, which can be used as an active layer of medical dressings. The optimised procedure was used in the production of porous medical dressings (Medisorb) on an industrial scale. In the industrial method, NaCl was used as a porophor agent in the solid form and as a 3% solution in polymer. The final materials were characterised by porosity and other functional parameters at the level recommended for medical dressings. Medisorb series materials do not show in vitro cytotoxic activity. |
format | Online Article Text |
id | pubmed-6317001 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-63170012019-01-08 Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters Draczynski, Zbigniew Kolesinska, Beata Latanska, Ilona Sujka, Witold Materials (Basel) Article A method for obtaining highly porous materials in the form of film, based on the butyric-acetic chitin co-polyesters, containing 90% of butyryl and 10% of acetyl groups, was developed. The highly porous films, with thickness up to 0.11 mm, were obtained by two methods: (a) pouring 5% BAC 90/10 solution in ethanol on the layer of solid salts (porophor agent) which after solidification was eluted with water; (b) application of the suspension of porophor agent in BAC 90/10 solution in the solvent mixture with density similar to bulk porophor agent. In the final stage, the materials were obtained with porosity up to 95–99% and tensile strength 5 cN, which can be used as an active layer of medical dressings. The optimised procedure was used in the production of porous medical dressings (Medisorb) on an industrial scale. In the industrial method, NaCl was used as a porophor agent in the solid form and as a 3% solution in polymer. The final materials were characterised by porosity and other functional parameters at the level recommended for medical dressings. Medisorb series materials do not show in vitro cytotoxic activity. MDPI 2018-11-23 /pmc/articles/PMC6317001/ /pubmed/30477125 http://dx.doi.org/10.3390/ma11122359 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Draczynski, Zbigniew Kolesinska, Beata Latanska, Ilona Sujka, Witold Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters |
title | Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters |
title_full | Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters |
title_fullStr | Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters |
title_full_unstemmed | Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters |
title_short | Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters |
title_sort | preparation method of porous dressing materials based on butyric-acetic chitin co-polyesters |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317001/ https://www.ncbi.nlm.nih.gov/pubmed/30477125 http://dx.doi.org/10.3390/ma11122359 |
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