Cargando…

Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters

A method for obtaining highly porous materials in the form of film, based on the butyric-acetic chitin co-polyesters, containing 90% of butyryl and 10% of acetyl groups, was developed. The highly porous films, with thickness up to 0.11 mm, were obtained by two methods: (a) pouring 5% BAC 90/10 solut...

Descripción completa

Detalles Bibliográficos
Autores principales: Draczynski, Zbigniew, Kolesinska, Beata, Latanska, Ilona, Sujka, Witold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317001/
https://www.ncbi.nlm.nih.gov/pubmed/30477125
http://dx.doi.org/10.3390/ma11122359
_version_ 1783384662046932992
author Draczynski, Zbigniew
Kolesinska, Beata
Latanska, Ilona
Sujka, Witold
author_facet Draczynski, Zbigniew
Kolesinska, Beata
Latanska, Ilona
Sujka, Witold
author_sort Draczynski, Zbigniew
collection PubMed
description A method for obtaining highly porous materials in the form of film, based on the butyric-acetic chitin co-polyesters, containing 90% of butyryl and 10% of acetyl groups, was developed. The highly porous films, with thickness up to 0.11 mm, were obtained by two methods: (a) pouring 5% BAC 90/10 solution in ethanol on the layer of solid salts (porophor agent) which after solidification was eluted with water; (b) application of the suspension of porophor agent in BAC 90/10 solution in the solvent mixture with density similar to bulk porophor agent. In the final stage, the materials were obtained with porosity up to 95–99% and tensile strength 5 cN, which can be used as an active layer of medical dressings. The optimised procedure was used in the production of porous medical dressings (Medisorb) on an industrial scale. In the industrial method, NaCl was used as a porophor agent in the solid form and as a 3% solution in polymer. The final materials were characterised by porosity and other functional parameters at the level recommended for medical dressings. Medisorb series materials do not show in vitro cytotoxic activity.
format Online
Article
Text
id pubmed-6317001
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-63170012019-01-08 Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters Draczynski, Zbigniew Kolesinska, Beata Latanska, Ilona Sujka, Witold Materials (Basel) Article A method for obtaining highly porous materials in the form of film, based on the butyric-acetic chitin co-polyesters, containing 90% of butyryl and 10% of acetyl groups, was developed. The highly porous films, with thickness up to 0.11 mm, were obtained by two methods: (a) pouring 5% BAC 90/10 solution in ethanol on the layer of solid salts (porophor agent) which after solidification was eluted with water; (b) application of the suspension of porophor agent in BAC 90/10 solution in the solvent mixture with density similar to bulk porophor agent. In the final stage, the materials were obtained with porosity up to 95–99% and tensile strength 5 cN, which can be used as an active layer of medical dressings. The optimised procedure was used in the production of porous medical dressings (Medisorb) on an industrial scale. In the industrial method, NaCl was used as a porophor agent in the solid form and as a 3% solution in polymer. The final materials were characterised by porosity and other functional parameters at the level recommended for medical dressings. Medisorb series materials do not show in vitro cytotoxic activity. MDPI 2018-11-23 /pmc/articles/PMC6317001/ /pubmed/30477125 http://dx.doi.org/10.3390/ma11122359 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Draczynski, Zbigniew
Kolesinska, Beata
Latanska, Ilona
Sujka, Witold
Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters
title Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters
title_full Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters
title_fullStr Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters
title_full_unstemmed Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters
title_short Preparation Method of Porous Dressing Materials Based on Butyric-Acetic Chitin Co-Polyesters
title_sort preparation method of porous dressing materials based on butyric-acetic chitin co-polyesters
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317001/
https://www.ncbi.nlm.nih.gov/pubmed/30477125
http://dx.doi.org/10.3390/ma11122359
work_keys_str_mv AT draczynskizbigniew preparationmethodofporousdressingmaterialsbasedonbutyricaceticchitincopolyesters
AT kolesinskabeata preparationmethodofporousdressingmaterialsbasedonbutyricaceticchitincopolyesters
AT latanskailona preparationmethodofporousdressingmaterialsbasedonbutyricaceticchitincopolyesters
AT sujkawitold preparationmethodofporousdressingmaterialsbasedonbutyricaceticchitincopolyesters