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Pacemaking in cardiac tissue. From IK2 to a coupled‐clock system
Initially, diastolic depolarization in Purkinje fibers was explained by deactivation of gK2 in the presence of inward current. Weakness of the hypothesis was a too negative reversal potential, sensitivity to external Na(+) ions, existence of K(+) depletion, and fake current during hyperpolarizing cl...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317064/ https://www.ncbi.nlm.nih.gov/pubmed/30604930 http://dx.doi.org/10.14814/phy2.13862 |