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HOXB8 enhances the proliferation and metastasis of colorectal cancer cells by promoting EMT via STAT3 activation

BACKGROUND: Previous studies have demonstrated that the expression of homeobox8 (HOXB8) is higher in colorectal cancer (CRC) tissues than in normal tissues; however, the precise role of HOXB8 in human CRC cells remains to be elucidated. METHODS: We generated lentiviral constructs to overexpress and...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Lin, Feiyan, Sun, Xuecheng, Jiang, Lei, Mao, Ruibo, Zhou, Shenyue, Shang, Wenjing, Bi, Ruichun, Lu, Fengying, Li, Shaotang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317211/
https://www.ncbi.nlm.nih.gov/pubmed/30622439
http://dx.doi.org/10.1186/s12935-018-0717-6

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