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Effect of Unit Cell Type and Pore Size on Porosity and Mechanical Behavior of Additively Manufactured Ti6Al4V Scaffolds
Porous metal structures have emerged as a promising solution in repairing and replacing damaged bone in biomedical applications. With the advent of additive manufacturing technology, fabrication of porous scaffold architecture of different unit cell types with desired parameters can replicate the bi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317238/ https://www.ncbi.nlm.nih.gov/pubmed/30487419 http://dx.doi.org/10.3390/ma11122402 |
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author | Zaharin, Haizum Aimi Abdul Rani, Ahmad Majdi Azam, Farooq I. Ginta, Turnad Lenggo Sallih, Nabihah Ahmad, Azlan Yunus, Nurul Azhani Zulkifli, Tun Zainal Azni |
author_facet | Zaharin, Haizum Aimi Abdul Rani, Ahmad Majdi Azam, Farooq I. Ginta, Turnad Lenggo Sallih, Nabihah Ahmad, Azlan Yunus, Nurul Azhani Zulkifli, Tun Zainal Azni |
author_sort | Zaharin, Haizum Aimi |
collection | PubMed |
description | Porous metal structures have emerged as a promising solution in repairing and replacing damaged bone in biomedical applications. With the advent of additive manufacturing technology, fabrication of porous scaffold architecture of different unit cell types with desired parameters can replicate the biomechanical properties of the natural bone, thereby overcoming the issues, such as stress shielding effect, to avoid implant failure. The purpose of this research was to investigate the influence of cube and gyroid unit cell types, with pore size ranging from 300 to 600 µm, on porosity and mechanical behavior of titanium alloy (Ti6Al4V) scaffolds. Scaffold samples were modeled and analyzed using finite element analysis (FEA) following the ISO standard (ISO 13314). Selective laser melting (SLM) process was used to manufacture five samples of each type. Morphological characterization of samples was performed through micro CT Scan system and the samples were later subjected to compression testing to assess the mechanical behavior of scaffolds. Numerical and experimental analysis of samples show porosity greater than 50% for all types, which is in agreement with desired porosity range of natural bone. Mechanical properties of samples depict that values of elastic modulus and yield strength decreases with increase in porosity, with elastic modulus reduced up to 3 GPa and yield strength decreased to 7 MPa. However, while comparing with natural bone properties, only cube and gyroid structure with pore size 300 µm falls under the category of giving similar properties to that of natural bone. Analysis of porous scaffolds show promising results for application in orthopedic implants. Application of optimum scaffold structures to implants can reduce the premature failure of implants and increase the reliability of prosthetics. |
format | Online Article Text |
id | pubmed-6317238 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-63172382019-01-08 Effect of Unit Cell Type and Pore Size on Porosity and Mechanical Behavior of Additively Manufactured Ti6Al4V Scaffolds Zaharin, Haizum Aimi Abdul Rani, Ahmad Majdi Azam, Farooq I. Ginta, Turnad Lenggo Sallih, Nabihah Ahmad, Azlan Yunus, Nurul Azhani Zulkifli, Tun Zainal Azni Materials (Basel) Article Porous metal structures have emerged as a promising solution in repairing and replacing damaged bone in biomedical applications. With the advent of additive manufacturing technology, fabrication of porous scaffold architecture of different unit cell types with desired parameters can replicate the biomechanical properties of the natural bone, thereby overcoming the issues, such as stress shielding effect, to avoid implant failure. The purpose of this research was to investigate the influence of cube and gyroid unit cell types, with pore size ranging from 300 to 600 µm, on porosity and mechanical behavior of titanium alloy (Ti6Al4V) scaffolds. Scaffold samples were modeled and analyzed using finite element analysis (FEA) following the ISO standard (ISO 13314). Selective laser melting (SLM) process was used to manufacture five samples of each type. Morphological characterization of samples was performed through micro CT Scan system and the samples were later subjected to compression testing to assess the mechanical behavior of scaffolds. Numerical and experimental analysis of samples show porosity greater than 50% for all types, which is in agreement with desired porosity range of natural bone. Mechanical properties of samples depict that values of elastic modulus and yield strength decreases with increase in porosity, with elastic modulus reduced up to 3 GPa and yield strength decreased to 7 MPa. However, while comparing with natural bone properties, only cube and gyroid structure with pore size 300 µm falls under the category of giving similar properties to that of natural bone. Analysis of porous scaffolds show promising results for application in orthopedic implants. Application of optimum scaffold structures to implants can reduce the premature failure of implants and increase the reliability of prosthetics. MDPI 2018-11-28 /pmc/articles/PMC6317238/ /pubmed/30487419 http://dx.doi.org/10.3390/ma11122402 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zaharin, Haizum Aimi Abdul Rani, Ahmad Majdi Azam, Farooq I. Ginta, Turnad Lenggo Sallih, Nabihah Ahmad, Azlan Yunus, Nurul Azhani Zulkifli, Tun Zainal Azni Effect of Unit Cell Type and Pore Size on Porosity and Mechanical Behavior of Additively Manufactured Ti6Al4V Scaffolds |
title | Effect of Unit Cell Type and Pore Size on Porosity and Mechanical Behavior of Additively Manufactured Ti6Al4V Scaffolds |
title_full | Effect of Unit Cell Type and Pore Size on Porosity and Mechanical Behavior of Additively Manufactured Ti6Al4V Scaffolds |
title_fullStr | Effect of Unit Cell Type and Pore Size on Porosity and Mechanical Behavior of Additively Manufactured Ti6Al4V Scaffolds |
title_full_unstemmed | Effect of Unit Cell Type and Pore Size on Porosity and Mechanical Behavior of Additively Manufactured Ti6Al4V Scaffolds |
title_short | Effect of Unit Cell Type and Pore Size on Porosity and Mechanical Behavior of Additively Manufactured Ti6Al4V Scaffolds |
title_sort | effect of unit cell type and pore size on porosity and mechanical behavior of additively manufactured ti6al4v scaffolds |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317238/ https://www.ncbi.nlm.nih.gov/pubmed/30487419 http://dx.doi.org/10.3390/ma11122402 |
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