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Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination

BACKGROUND: The 5 hydroxymethylation (5hmC) mark and TET DNA dioxygenases play a pivotal role in embryonic stem cell differentiation and animal development. However, very little is known about TET enzymes in lineage determination of human bone marrow-derived mesenchymal stem/stromal cells (BMSC). We...

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Detalles Bibliográficos
Autores principales: Cakouros, Dimitrios, Hemming, Sarah, Gronthos, Kahlia, Liu, Renjing, Zannettino, Andrew, Shi, Songtao, Gronthos, Stan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317244/
https://www.ncbi.nlm.nih.gov/pubmed/30606231
http://dx.doi.org/10.1186/s13072-018-0247-4