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Controlled intracellular trafficking alleviates an expression bottleneck in S. cerevisiae ester biosynthesis

In metabolic engineering, most available pathway engineering strategies aim to control enzyme expression by making changes at the transcriptional level with an underlying assumption that translation and functional expression follow suit. In this work, we engineer expression of a key reaction step in...

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Detalles Bibliográficos
Autores principales: Zhu, Jie, Schwartz, Cory, Wheeldon, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317282/
https://www.ncbi.nlm.nih.gov/pubmed/30622894
http://dx.doi.org/10.1016/j.mec.2018.e00085