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IRF1 inhibits the proliferation and metastasis of colorectal cancer by suppressing the RAS-RAC1 pathway

BACKGROUND: Interferon regulatory factor 1 (IRF1) plays a role in the immune response, cellular necrosis, DNA damage, and DNA repair, offering an attractive target for anticancer treatment. However, little is known about the role of IRF1 in the regulation of CRC progression. METHODS: Quantitative re...

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Detalles Bibliográficos
Autores principales:	Hong, Min, Zhang, Zuoyang, Chen, Qing, Lu, Yanxia, Zhang, Jianming, Lin, Chun, Zhang, Fan, Zhang, Wenjuan, Li, Xiaomin, Zhang, Wei, Li, Xuenong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317468/ https://www.ncbi.nlm.nih.gov/pubmed/30643462 http://dx.doi.org/10.2147/CMAR.S186236

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