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Astragaloside IV ameliorates high glucose-induced renal tubular epithelial-mesenchymal transition by blocking mTORC1/p70S6K signaling in HK-2 cells

Astragaloside IV (AST) is the major active saponin in Astragalus membranaceus and, reportedly, has a variety of pharmacological activities. However, the potential of AST to ameliorate high glucose-mediated renal tubular epithelial-mesenchymal transition (EMT) remains undetermined. The aim of the pre...

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Detalles Bibliográficos
Autores principales:	Chen, Xiao, Yang, Yang, Liu, Chenxu, Chen, Zhigao, Wang, Dongdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317658/ https://www.ncbi.nlm.nih.gov/pubmed/30483732 http://dx.doi.org/10.3892/ijmm.2018.3999

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