Cargando…

Atorvastatin downregulates HSP22 expression in an atherosclerotic model in vitro and in vivo

One of the pathological functions of heat shock protein 22 (HSP22) is the association with inflammatory diseases and atherosclerosis. However, the effects of a high-fat diet (HFD) or oxidized low-density lipoprotein (ox-LDL) combined with atorvastatin (ATV) on HSP22 expression are entirely unknown....

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Qi, Xiang, Jian, Gong, Ren, Fang, Hai-Yang, Xu, Cong-Cong, Zhang, Hong-Zhou, Wu, Yan-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317682/ https://www.ncbi.nlm.nih.gov/pubmed/30535427 http://dx.doi.org/10.3892/ijmm.2018.4015

Ejemplares similares

Atorvastatin protects against contrast-induced nephropathy via anti-apoptosis by the upregulation of Hsp27 in vivo and in vitro
por: He, Xuyu, et al.
Publicado: (2017)

Experimental study of USPIO-enhanced MRI in the detection of atherosclerotic plaque and the intervention of atorvastatin
por: SHA, TING, et al.
Publicado: (2016)

Role of heat shock protein 22 in the protective effect of geranylgeranylacetone in response to oxidized-LDL
por: Gong, Ren, et al.
Publicado: (2019)

Anti-atherosclerotic function of Astragali Radix extract: downregulation of adhesion molecules in vitro and in vivo
por: You, Yang, et al.
Publicado: (2012)

Di’ao Xinxuekang Capsule Improves the Anti-Atherosclerotic Effect of Atorvastatin by Downregulating the SREBP2/PCSK9 Signalling Pathway
por: Liang, Jiyi, et al.
Publicado: (2022)

Atorvastatin Downregulates In Vitro Methyl Methanesulfonate and Cyclophosphamide Alkylation-Mediated Cellular and DNA Injuries
por: Araujo-Lima, Carlos F., et al.
Publicado: (2018)

Downregulation of both gene expression and activity of Hsp27 improved maturation of mouse oocyte in vitro
por: Liu, Jin-Juan, et al.
Publicado: (2010)

In vivo and In vitro Drug Interactions Study of Glimepride with Atorvastatin and Rosuvastatin
por: Galani, VJ, et al.
Publicado: (2010)

Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation
por: Sezer, Ebru Demirel, et al.
Publicado: (2011)

Add-On Effect of Probucol in Atherosclerotic, Cholesterol-Fed Rabbits Treated with Atorvastatin
por: Keyamura, Yuka, et al.
Publicado: (2014)

Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E–knockout mice
por: Li, Gang, et al.
Publicado: (2014)

Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or Atorvastatin
por: Ekstrand, Matias, et al.
Publicado: (2015)

Atorvastatin Therapy Modulates Telomerase Activity in Patients Free of Atherosclerotic Cardiovascular Diseases
por: Strazhesko, Irina D., et al.
Publicado: (2016)

Development of the Binary and Ternary Atorvastatin Solid Dispersions: In Vitro and In Vivo Investigations
por: Faraji, Elahe, et al.
Publicado: (2021)

Identifying Vulnerable Atherosclerotic Plaque in Rabbits Using DMSA-USPIO Enhanced Magnetic Resonance Imaging to Investigate the Effect of Atorvastatin
por: Qi, Chunmei, et al.
Publicado: (2015)

ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro
por: Song, Lei, et al.
Publicado: (2020)

Atorvastatin Inhibits Inflammatory Response, Attenuates Lipid Deposition, and Improves the Stability of Vulnerable Atherosclerotic Plaques by Modulating Autophagy
por: Peng, Shi, et al.
Publicado: (2018)

Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD4
por: Song, Xiang-Yuan, et al.
Publicado: (2022)

Comparing the combination therapy of ezetimibe and atorvastatin with atorvastatin monotherapy for regulating blood lipids: a systematic review and meta-analyse
por: Ai, Cong, et al.
Publicado: (2018)

Solubility and Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin: In Vitro, Ex Vivo, and In Vivo Studies
por: Rodde, Madhuri S., et al.
Publicado: (2014)

Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo
por: Tran, Phan LCHB, et al.
Publicado: (2010)

The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo
por: Li, Zhenbao, et al.
Publicado: (2017)

Formulation of Modified-Release Bilayer Tablets of Atorvastatin and Ezetimibe: An In-Vitro and In-Vivo Analysis
por: Mubeen, Iqra, et al.
Publicado: (2022)

Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo
por: Nowak, Witold N., et al.
Publicado: (2019)

Atorvastatin Attenuates Metabolic Remodeling in Ischemic Myocardium through the Downregulation of UCP2 Expression
por: Yang, Chunyan, et al.
Publicado: (2018)

Atorvastatin attenuates plaque vulnerability by downregulation of EMMPRIN expression via COX-2/PGE2 pathway
por: Liang, Xing, et al.
Publicado: (2017)

Effects of atorvastatin on serum lipids, serum inflammation and plaque morphology in patients with stable atherosclerotic plaques
por: GUO, SUXIA, et al.
Publicado: (2012)

Depot injectable atorvastatin biodegradable in situ gel: development, optimization, in vitro, and in vivo evaluation
por: Ahmed, Tarek A, et al.
Publicado: (2016)

An ivermectin – atorvastatin combination impairs nuclear transport inhibiting dengue infection in vitro and in vivo
por: Palacios-Rápalo, Selvin Noé, et al.
Publicado: (2023)

Antidepressant Effects of Abscisic Acid Mediated by the Downregulation of Corticotrophin-Releasing Hormone Gene Expression in Rats
por: Qi, Cong-Cong, et al.
Publicado: (2014)

Baicalin increases developmental competence of mouse embryos in vitro by inhibiting cellular apoptosis and modulating HSP70 and DNMT expression
por: QI, Xiaonan, et al.
Publicado: (2016)

Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo
por: Yan, Zhen, et al.
Publicado: (2017)

Atorvastatin downregulates co-inhibitory receptor expression by targeting Ras-activated mTOR signalling
por: Okoye, Isobel, et al.
Publicado: (2017)

Use of Atorvastatin in Lipid Disorders and Cardiovascular Disease in Chinese Patients
por: Ye, Yi-Cong, et al.
Publicado: (2015)

The Complementary Effects of Atorvastatin and Exercise Treatment on the Composition and Stability of the Atherosclerotic Plaques in ApoE Knockout Mice
por: Moustardas, Petros, et al.
Publicado: (2014)

Atorvastatin: In-Vivo Synergy with Metronidazole as Anti-Blastocystis Therapy
por: Basyoni, Maha M. A., et al.
Publicado: (2018)

A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo
por: Wu, Yi-Wen, et al.
Publicado: (2021)

Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells
por: Cong, Lin, et al.
Publicado: (2018)

Inhibition of Axitinib on Buspirone Metabolism in vitro and in vivo
por: Zhang, Bo-Wen, et al.
Publicado: (2022)

Augmented Anticancer Effects of Cantharidin with Liposomal Encapsulation: In Vitro and In Vivo Evaluation
por: Zhang, Xue, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2a6e8c2no3i1dj8a5le0h7jh9j