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Visual field defects and changes in central retinal artery occlusion

OBJECTIVES: To investigate the characteristics and temporal changes in visual field defects (VFDs) in eyes with acute central retinal artery occlusion (CRAO). DESIGN: Retrospective, observational case series METHODS: A total of 119 patients diagnosed with acute non-arteritic CRAO through examination...

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Autores principales: Kim, Hyeong Min, Park, Young Joo, Park, Kyu Hyung, Woo, Se Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317808/
https://www.ncbi.nlm.nih.gov/pubmed/30605464
http://dx.doi.org/10.1371/journal.pone.0209118
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author Kim, Hyeong Min
Park, Young Joo
Park, Kyu Hyung
Woo, Se Joon
author_facet Kim, Hyeong Min
Park, Young Joo
Park, Kyu Hyung
Woo, Se Joon
author_sort Kim, Hyeong Min
collection PubMed
description OBJECTIVES: To investigate the characteristics and temporal changes in visual field defects (VFDs) in eyes with acute central retinal artery occlusion (CRAO). DESIGN: Retrospective, observational case series METHODS: A total of 119 patients diagnosed with acute non-arteritic CRAO through examination with Goldmann perimetry were included among the patients who visited Seoul National University Bundang Hospital between January 2009 and December 2016. They were treated with either conservative treatments or intra-arterial thrombolysis (IAT). The baseline features and temporal changes of visual field examination results and the association with clinical parameters including visual acuity, optical coherence tomography (OCT) findings, and the CRAO stages. RESULTS: All of the 119 patients showed visual field defect and suffered unilateral acute CRAO. We observed five characteristic VFDs: peripheral constriction only (8%), paracentral scotoma (3%), central and cecocentral scotoma (19%), temporal island (59%), and no visual field (10%). Severe VFDs were associated with severe CRAO stages, poor baseline BCVA, delayed retinal arterial perfusion, and severe retinal morphologic changes on OCT. We found improvements in the visual field in 39% of all cases during the follow-up periods. Mild CRAO stages, good baseline BCVA, mild retinal morphologic changes, and mild initial VFDs were significantly associated with visual field improvement. CONCLUSIONS: The five characteristic types of VFDs and their improvement in eyes with CRAO are associated with baseline features related to the severity of retinal ischemia. We suggest that the underlying mechanisms of VFDs involve the balance between the retinal arterial perfusion and the ischemic vulnerability of each retinal area.
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spelling pubmed-63178082019-01-19 Visual field defects and changes in central retinal artery occlusion Kim, Hyeong Min Park, Young Joo Park, Kyu Hyung Woo, Se Joon PLoS One Research Article OBJECTIVES: To investigate the characteristics and temporal changes in visual field defects (VFDs) in eyes with acute central retinal artery occlusion (CRAO). DESIGN: Retrospective, observational case series METHODS: A total of 119 patients diagnosed with acute non-arteritic CRAO through examination with Goldmann perimetry were included among the patients who visited Seoul National University Bundang Hospital between January 2009 and December 2016. They were treated with either conservative treatments or intra-arterial thrombolysis (IAT). The baseline features and temporal changes of visual field examination results and the association with clinical parameters including visual acuity, optical coherence tomography (OCT) findings, and the CRAO stages. RESULTS: All of the 119 patients showed visual field defect and suffered unilateral acute CRAO. We observed five characteristic VFDs: peripheral constriction only (8%), paracentral scotoma (3%), central and cecocentral scotoma (19%), temporal island (59%), and no visual field (10%). Severe VFDs were associated with severe CRAO stages, poor baseline BCVA, delayed retinal arterial perfusion, and severe retinal morphologic changes on OCT. We found improvements in the visual field in 39% of all cases during the follow-up periods. Mild CRAO stages, good baseline BCVA, mild retinal morphologic changes, and mild initial VFDs were significantly associated with visual field improvement. CONCLUSIONS: The five characteristic types of VFDs and their improvement in eyes with CRAO are associated with baseline features related to the severity of retinal ischemia. We suggest that the underlying mechanisms of VFDs involve the balance between the retinal arterial perfusion and the ischemic vulnerability of each retinal area. Public Library of Science 2019-01-03 /pmc/articles/PMC6317808/ /pubmed/30605464 http://dx.doi.org/10.1371/journal.pone.0209118 Text en © 2019 Kim et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kim, Hyeong Min
Park, Young Joo
Park, Kyu Hyung
Woo, Se Joon
Visual field defects and changes in central retinal artery occlusion
title Visual field defects and changes in central retinal artery occlusion
title_full Visual field defects and changes in central retinal artery occlusion
title_fullStr Visual field defects and changes in central retinal artery occlusion
title_full_unstemmed Visual field defects and changes in central retinal artery occlusion
title_short Visual field defects and changes in central retinal artery occlusion
title_sort visual field defects and changes in central retinal artery occlusion
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317808/
https://www.ncbi.nlm.nih.gov/pubmed/30605464
http://dx.doi.org/10.1371/journal.pone.0209118
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