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Meiosis-specific prophase-like pathway controls cleavage-independent release of cohesin by Wapl phosphorylation

Sister chromatid cohesion on chromosome arms is essential for the segregation of homologous chromosomes during meiosis I while it is dispensable for sister chromatid separation during mitosis. It was assumed that, unlike the situation in mitosis, chromosome arms retain cohesion prior to onset of ana...

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Detalles Bibliográficos
Autores principales: Challa, Kiran, Fajish V, Ghanim, Shinohara, Miki, Klein, Franz, Gasser, Susan M., Shinohara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317811/
https://www.ncbi.nlm.nih.gov/pubmed/30605471
http://dx.doi.org/10.1371/journal.pgen.1007851