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Vanishing Bile Duct Syndrome in a Patient with Uterine Cancer and Paraneoplastic Systemic Sclerosis

Vanishing bile duct syndrome (VBDS) is a rare entity of acquired disorders resulting in cholestasis secondary to progressive destruction of intrahepatic bile ducts. The syndrome has been described in the setting of autoimmune disorders, medication toxicities, genetic disorders, infectious etiologies...

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Detalles Bibliográficos
Autores principales: Sedhom, Daniel, Herrmann, Amanda, D’Souza, Melroy, Fyfe, Billie, Zaldana, Francisco, Schlesinger, Naomi, Rustgi, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317838/
https://www.ncbi.nlm.nih.gov/pubmed/30643839
http://dx.doi.org/10.14309/crj.2018.95
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author Sedhom, Daniel
Herrmann, Amanda
D’Souza, Melroy
Fyfe, Billie
Zaldana, Francisco
Schlesinger, Naomi
Rustgi, Vinod
author_facet Sedhom, Daniel
Herrmann, Amanda
D’Souza, Melroy
Fyfe, Billie
Zaldana, Francisco
Schlesinger, Naomi
Rustgi, Vinod
author_sort Sedhom, Daniel
collection PubMed
description Vanishing bile duct syndrome (VBDS) is a rare entity of acquired disorders resulting in cholestasis secondary to progressive destruction of intrahepatic bile ducts. The syndrome has been described in the setting of autoimmune disorders, medication toxicities, genetic disorders, infectious etiologies, and in rare cases, neoplastic processes. There are no known case reports of VBDS in the setting of uterine malignancy. We present a case of VBDS in a patient with underlying uterine cancer complicated by paraneoplastic systemic sclerosis.
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spelling pubmed-63178382019-01-14 Vanishing Bile Duct Syndrome in a Patient with Uterine Cancer and Paraneoplastic Systemic Sclerosis Sedhom, Daniel Herrmann, Amanda D’Souza, Melroy Fyfe, Billie Zaldana, Francisco Schlesinger, Naomi Rustgi, Vinod ACG Case Rep J Case Report Vanishing bile duct syndrome (VBDS) is a rare entity of acquired disorders resulting in cholestasis secondary to progressive destruction of intrahepatic bile ducts. The syndrome has been described in the setting of autoimmune disorders, medication toxicities, genetic disorders, infectious etiologies, and in rare cases, neoplastic processes. There are no known case reports of VBDS in the setting of uterine malignancy. We present a case of VBDS in a patient with underlying uterine cancer complicated by paraneoplastic systemic sclerosis. American College of Gastroenterology 2018-12-19 /pmc/articles/PMC6317838/ /pubmed/30643839 http://dx.doi.org/10.14309/crj.2018.95 Text en Copyright © Sedhom et al. This is an open-access article. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Case Report
Sedhom, Daniel
Herrmann, Amanda
D’Souza, Melroy
Fyfe, Billie
Zaldana, Francisco
Schlesinger, Naomi
Rustgi, Vinod
Vanishing Bile Duct Syndrome in a Patient with Uterine Cancer and Paraneoplastic Systemic Sclerosis
title Vanishing Bile Duct Syndrome in a Patient with Uterine Cancer and Paraneoplastic Systemic Sclerosis
title_full Vanishing Bile Duct Syndrome in a Patient with Uterine Cancer and Paraneoplastic Systemic Sclerosis
title_fullStr Vanishing Bile Duct Syndrome in a Patient with Uterine Cancer and Paraneoplastic Systemic Sclerosis
title_full_unstemmed Vanishing Bile Duct Syndrome in a Patient with Uterine Cancer and Paraneoplastic Systemic Sclerosis
title_short Vanishing Bile Duct Syndrome in a Patient with Uterine Cancer and Paraneoplastic Systemic Sclerosis
title_sort vanishing bile duct syndrome in a patient with uterine cancer and paraneoplastic systemic sclerosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317838/
https://www.ncbi.nlm.nih.gov/pubmed/30643839
http://dx.doi.org/10.14309/crj.2018.95
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