Pentraxin 3 deletion aggravates allergic inflammation through a T(H)17-dominant phenotype and enhanced CD4 T-cell survival

BACKGROUND: Pentraxin 3 (PTX3) is a multifunctional molecule that plays a nonredundant role at the crossroads between pathogen clearance, innate immune system, matrix deposition, female fertility, and vascular biology. It is produced at sites of infection and inflammation by both structural and infl...

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Detalles Bibliográficos
Autores principales: Balhara, Jyoti, Shan, Lianyu, Zhang, Jingbo, Muhuri, Anik, Halayko, Andrew J., Almiski, Muhamad S., Doeing, Diana, McConville, John, Matzuk, Martin M., Gounni, Abdelilah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Academy of Allergy, Asthma & Immunology 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317853/
https://www.ncbi.nlm.nih.gov/pubmed/27567326
http://dx.doi.org/10.1016/j.jaci.2016.04.063

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