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Piezo’s membrane footprint and its contribution to mechanosensitivity
Piezo1 is an ion channel that gates open when mechanical force is applied to a cell membrane, thus allowing cells to detect and respond to mechanical stimulation. Molecular structures of Piezo1 reveal a large ion channel with an unusually curved shape. This study analyzes how such a curved ion chann...
Autores principales: | Haselwandter, Christoph A, MacKinnon, Roderick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317911/ https://www.ncbi.nlm.nih.gov/pubmed/30480546 http://dx.doi.org/10.7554/eLife.41968 |
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