Cargando…

2′‐Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation

Inhibition of the signal transducer and activator of transcription 3 (STAT3) signaling pathway is a novel therapeutic strategy to treat human cancers with constitutively active STAT3. During the screening of natural products to find STAT3 inhibitors, we identified 2′‐hydroxycinnamaldehyde (HCA) as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Yae Jin, Kim, Young‐Hwan, Lee, Yu‐Jin, Choi, Jiyeon, Kim, Cheol‐Hee, Han, Dong Cho, Kwon, Byoung‐Mog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317917/
https://www.ncbi.nlm.nih.gov/pubmed/30375708
http://dx.doi.org/10.1111/cas.13852

Ejemplares similares