Cargando…
2′‐Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation
Inhibition of the signal transducer and activator of transcription 3 (STAT3) signaling pathway is a novel therapeutic strategy to treat human cancers with constitutively active STAT3. During the screening of natural products to find STAT3 inhibitors, we identified 2′‐hydroxycinnamaldehyde (HCA) as a...
Autores principales: | Yoon, Yae Jin, Kim, Young‐Hwan, Lee, Yu‐Jin, Choi, Jiyeon, Kim, Cheol‐Hee, Han, Dong Cho, Kwon, Byoung‐Mog |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317917/ https://www.ncbi.nlm.nih.gov/pubmed/30375708 http://dx.doi.org/10.1111/cas.13852 |
Ejemplares similares
-
2′-Hydroxycinnamaldehyde ameliorates imiquimod-induced psoriasiform inflammation by targeting PKM2-STAT3 signaling in mice
por: Hao, Lihua, et al.
Publicado: (2021) -
(E)-2-Hydroxycinnamaldehyde
por: Kang, Ki-Tae, et al.
Publicado: (2013) -
Regulation of ROS-Dependent JNK Pathway by 2’-Hydroxycinnamaldehyde Inducing Apoptosis in Human Promyelocytic HL-60 Leukemia Cells
por: Chung, Kyung-Sook, et al.
Publicado: (2021) -
Acacetin Inhibits the Growth of STAT3-Activated DU145 Prostate Cancer Cells by Directly Binding to Signal Transducer and Activator of Transcription 3 (STAT3)
por: Yun, Sun, et al.
Publicado: (2021) -
Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex
por: Choi, Jiyeon, et al.
Publicado: (2019)