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Antibiotics suppress colon tumorigenesis through inhibition of aberrant DNA methylation in an azoxymethane and dextran sulfate sodium colitis model
Chronic inflammation is involved in the development of colon cancer by inducing mutations and aberrant DNA methylation in colon epithelial cells. Furthermore, there is growing evidence that colonic microbiota modulates the inflammation response in the host and influences colon tumorigenesis. However...
Autores principales: | Hattori, Naoko, Niwa, Tohru, Ishida, Tatsuya, Kobayashi, Kyosuke, Imai, Toshio, Mori, Akiko, Kimura, Kana, Mori, Takeshi, Asami, Yukio, Ushijima, Toshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317928/ https://www.ncbi.nlm.nih.gov/pubmed/30443963 http://dx.doi.org/10.1111/cas.13880 |
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