Mutational activation of the epidermal growth factor receptor down‐regulates major histocompatibility complex class I expression via the extracellular signal‐regulated kinase in non–small cell lung cancer

The efficacy of programmed cell death–1 (PD‐1) blockade in patients with non–small cell lung cancer (NSCLC) positive for epidermal growth factor receptor (EGFR) gene mutations has been found to be limited, but the underlying mechanisms for this poor response have remained obscure. Given that the rec...

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Detalles Bibliográficos
Autores principales: Watanabe, Satomi, Hayashi, Hidetoshi, Haratani, Koji, Shimizu, Shigeki, Tanizaki, Junko, Sakai, Kazuko, Kawakami, Hisato, Yonesaka, Kimio, Tsurutani, Junji, Togashi, Yosuke, Nishio, Kazuto, Ito, Akihiko, Nakagawa, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317949/
https://www.ncbi.nlm.nih.gov/pubmed/30390416
http://dx.doi.org/10.1111/cas.13860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317949/
https://www.ncbi.nlm.nih.gov/pubmed/30390416
http://dx.doi.org/10.1111/cas.13860

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