All‐trans retinoic acid reverses epithelial‐mesenchymal transition in paclitaxel‐resistant cells by inhibiting nuclear factor kappa B and upregulating gap junctions

Paclitaxel is a widely used chemotherapy drug, but development of resistance leads to treatment failure. Tumor cells that are treated with a sublethal dose of paclitaxel for a long period of time show the epithelial‐mesenchymal transition (EMT) phenotype, which leads to metastasis and resistance. Al...

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Detalles Bibliográficos
Autores principales: Shi, Guiling, Zheng, Xiaoli, Wu, Xiaojing, Wang, Siqi, Wang, Yijia, Xing, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317959/
https://www.ncbi.nlm.nih.gov/pubmed/30375704
http://dx.doi.org/10.1111/cas.13855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317959/
https://www.ncbi.nlm.nih.gov/pubmed/30375704
http://dx.doi.org/10.1111/cas.13855

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