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Structure of BAI1/ELMO2 complex reveals an action mechanism of adhesion GPCRs via ELMO family scaffolds
The brain-specific angiogenesis inhibitor (BAI) subfamily of adhesion G protein-coupled receptors (aGPCRs) plays crucial roles in diverse cellular processes including phagocytosis, myoblast fusion, and synaptic development through the ELMO/DOCK/Rac signaling pathway, although the underlying molecula...
Autores principales: | Weng, Zhuangfeng, Situ, Chenghao, Lin, Lin, Wu, Zhenguo, Zhu, Jinwei, Zhang, Rongguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318265/ https://www.ncbi.nlm.nih.gov/pubmed/30604775 http://dx.doi.org/10.1038/s41467-018-07938-9 |
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