A novel m(6)A reader Prrc2a controls oligodendroglial specification and myelination

While N(6)-methyladenosine (m(6)A), the most abundant internal modification in eukaryotic mRNA, is linked to cell differentiation and tissue development, the biological significance of m(6)A modification in mammalian glial development remains unknown. Here, we identify a novel m(6)A reader, Prrc2a (...

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Detalles Bibliográficos
Autores principales: Wu, Rong, Li, Ang, Sun, Baofa, Sun, Jian-Guang, Zhang, Jinhua, Zhang, Ting, Chen, Yusheng, Xiao, Yujie, Gao, Yuhao, Zhang, Qingyang, Ma, Jun, Yang, Xin, Liao, Yajin, Lai, Wei-Yi, Qi, Xiaolong, Wang, Shukun, Shu, Yousheng, Wang, Hai-Lin, Wang, Fengchao, Yang, Yun-Gui, Yuan, Zengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318280/
https://www.ncbi.nlm.nih.gov/pubmed/30514900
http://dx.doi.org/10.1038/s41422-018-0113-8

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