Expansion and differentiation of human hepatocyte-derived liver progenitor-like cells and their use for the study of hepatotropic pathogens

The study of pathophysiological mechanisms in human liver disease has been constrained by the inability to expand primary hepatocytes in vitro while maintaining proliferative capacity and metabolic function. We and others have previously shown that mouse mature hepatocytes can be converted to liver...

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Detalles Bibliográficos
Autores principales: Fu, Gong-Bo, Huang, Wei-Jian, Zeng, Min, Zhou, Xu, Wu, Hong-Ping, Liu, Chang-Cheng, Wu, Han, Weng, Jun, Zhang, Hong-Dan, Cai, Yong-Chao, Ashton, Charles, Ding, Min, Tang, Dan, Zhang, Bao-Hua, Gao, Yi, Yu, Wei-Feng, Zhai, Bo, He, Zhi-Ying, Wang, Hong-Yang, Yan, He-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318298/
https://www.ncbi.nlm.nih.gov/pubmed/30361550
http://dx.doi.org/10.1038/s41422-018-0103-x

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