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Molecular signatures of multiple myeloma progression through single cell RNA-Seq

We used single cell RNA-Seq to examine molecular heterogeneity in multiple myeloma (MM) in 597 CD138 positive cells from bone marrow aspirates of 15 patients at different stages of disease progression. 790 genes were selected by coefficient of variation (CV) method and organized cells into four grou...

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Detalles Bibliográficos
Autores principales: Jang, Jin Sung, Li, Ying, Mitra, Amit Kumar, Bi, Lintao, Abyzov, Alexej, van Wijnen, Andre J., Baughn, Linda B., Van Ness, Brian, Rajkumar, Vincent, Kumar, Shaji, Jen, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318319/
https://www.ncbi.nlm.nih.gov/pubmed/30607001
http://dx.doi.org/10.1038/s41408-018-0160-x