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Molecular signatures of multiple myeloma progression through single cell RNA-Seq
We used single cell RNA-Seq to examine molecular heterogeneity in multiple myeloma (MM) in 597 CD138 positive cells from bone marrow aspirates of 15 patients at different stages of disease progression. 790 genes were selected by coefficient of variation (CV) method and organized cells into four grou...
Autores principales: | Jang, Jin Sung, Li, Ying, Mitra, Amit Kumar, Bi, Lintao, Abyzov, Alexej, van Wijnen, Andre J., Baughn, Linda B., Van Ness, Brian, Rajkumar, Vincent, Kumar, Shaji, Jen, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318319/ https://www.ncbi.nlm.nih.gov/pubmed/30607001 http://dx.doi.org/10.1038/s41408-018-0160-x |
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