高频胸壁振荡排痰仪对单孔胸腔镜肺叶切除术后肺功能的影响

BACKGROUND AND OBJECTIVE: It has been confirmed that high-frequency chest wall oscillatory (HFCWO) is a new type of auxiliary sputum discharge device. However, up to now, the specific therapeutic effect of HFCWO is still uncertain. This study aimed to compare the changes of the sputum volume before and after the treatment of HFCWO, and to investigate the effect of HFCWO on lung function and arterial blood gas analysis after single port video-assisted thoracoscopic surgery lobectomy (S-VATS). METHODS: A total of 90 patients with S-VATS lobectomy were collected in the Second Affiliated Hospital of Soochow University from January 2017 to December 2017, which were randomly divided into the experimental group with HFCWO (n=45) and the control group (n=45) with routine clapping, respectively. The sputum volume of the two groups was measured 5 days before operation. Lung function and arterial blood gas analysis was measured before and 7(th) days after surgery. RESULTS: The sputum volume was higher in the experimental group than that of the control group after surgery, there was statistically significant difference for the first three days (P < 0.05). There was no statistically significant difference between the two groups in forced expiratory volume in one second (FEV(1)), forced vital capacity (FVC) and oxygen partial pressure (PaO(2)) before surgery (P > 0.05); Compared with those before surgery, FEV(1), FVC and PaO(2) decreased in both groups after surgery (P < 0.05); However, FEV(1), FVC and PaO(2) in the experimental group were higher than those in the control group (P < 0.05); There was no statistically significant difference in preoperative and postoperative partial pressure of carbon dioxide (PaCO(2)) between the two groups (P > 0.05). CONCLUSION: HFCWO can significantly increase the amount of sputum excretion, improve lung function and alleviate hypoxia status after S-VATS lobectomy. This study provides a promising approach for HFCWO toward hypoxia status after S-VATS lobectomy.