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Peptide Drug Release Behavior from Biodegradable Temperature-Responsive Injectable Hydrogels Exhibiting Irreversible Gelation

We investigated the release behavior of glucagon-like peptide-1 (GLP-1) from a biodegradable injectable polymer (IP) hydrogel. This hydrogel shows temperature-responsive irreversible gelation due to the covalent bond formation through a thiol-ene reaction. In vitro sustained release of GLP-1 from an...

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Detalles Bibliográficos
Autores principales:	Takata, Kazuyuki, Takai, Hiroki, Yoshizaki, Yuta, Nagata, Takuya, Kawahara, Keisuke, Yoshida, Yasuyuki, Kuzuya, Akinori, Ohya, Yuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318690/ https://www.ncbi.nlm.nih.gov/pubmed/30920533 http://dx.doi.org/10.3390/gels3040038

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