Cargando…

A case of KMT2A–SEPT9 fusion–associated acute megakaryoblastic leukemia

Acute megakaryoblastic leukemia (AMKL) constitutes ∼5%–15% of cases of non–Down syndrome AML in children, and in the majority of cases, chimeric oncogenes resulting from recurrent gene rearrangements are identified. Based on these rearrangements, several molecular subsets have been characterized pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Forlenza, Christopher J., Zhang, Yanming, Yao, JinJuan, Benayed, Ryma, Steinherz, Peter, Ramaswamy, Kavitha, Kessel, Rachel, Roshal, Mikhail, Shukla, Neerav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Rapid Cancer Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318764/ https://www.ncbi.nlm.nih.gov/pubmed/30455225 http://dx.doi.org/10.1101/mcs.a003426

Ejemplares similares

Clofarabine with topotecan, vinorelbine, and thiotepa reinduction regimen for children and young adults with relapsed AML
por: Ramaswamy, Kavitha, et al.
Publicado: (2022)

Acute myeloid leukemia with an MN1-ETV6 fusion in a young child with Down syndrome
por: Rosenzweig, Jaclyn, et al.
Publicado: (2022)

A novel acquired EGFR-SEPT14 fusion confers differential drug resistance to EGFR inhibitors in lung adenocarcinoma
por: Wang, Weidong, et al.
Publicado: (2023)

JAK2V617F and p53 mutations coexist in erythroleukemia and megakaryoblastic leukemic cell lines
por: Zhao, Wanke, et al.
Publicado: (2012)

Myeloid/lymphoid neoplasms with eosinophilia/basophilia and ETV6-ABL1 fusion: cell-of-origin and response to tyrosine kinase inhibition
por: Yao, Jinjuan, et al.
Publicado: (2020)

The effect of amifostine on differentiation of the human megakaryoblastic Dami cell line
por: Wang, Hai‐tao, et al.
Publicado: (2016)

Acute myeloid leukemia with KMT2A-SEPT5 translocation: A case report and review of the literature
por: Elzamly, Shaimaa, et al.
Publicado: (2018)

Successful treatment and integrated genomic analysis of an infant with FIP1L1-RARA fusion–associated myeloid neoplasm
por: Miltiadous, Oriana, et al.
Publicado: (2022)

Germline BRCA2 mutations detected in pediatric sequencing studies impact parents’ evaluation and care
por: Walsh, Michael F., et al.
Publicado: (2017)

Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL
por: Kang, Huining, et al.
Publicado: (2018)

Clinical profile in KMT2A-SEPT6-positive acute myeloid leukemia: Does it often co-occur with NRAS mutations?
por: Chen, Fang, et al.
Publicado: (2022)

An Unusual Case of Myeloperoxidase-Positive Acute Megakaryoblastic Leukemia
por: Lee, Hyeyoung, et al.
Publicado: (2015)

Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma
por: Kawasaki, Yukako, et al.
Publicado: (2015)

Targeting SLMAP-ALK—a novel gene fusion in lung adenocarcinoma
por: Pagan, Carlos, et al.
Publicado: (2019)

Detection of a GLIS3 fusion in an infant with AML refractory to chemotherapy
por: Smith, Stephen M., et al.
Publicado: (2022)

Acute Megakaryoblastic Leukemia Harboring a Subclone Expressing BCR-ABL1 Fusion Gene Product
por: Kashima, Emiko, et al.
Publicado: (2021)

A novel, potentially targetable TMEM106B-BRAF fusion in pleomorphic xanthoastrocytoma
por: Hsiao, Susan J., et al.
Publicado: (2017)

Diffuse midline glioma with novel, potentially targetable, FGFR2–VPS35 fusion
por: Zanazzi, George, et al.
Publicado: (2020)

P2RY8-CRLF2 Fusion–Positive Acute Myeloid Leukemia With Myelodysplasia-Related Changes: Response to Novel Therapy
por: Aypar, Umut, et al.
Publicado: (2020)

Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant
por: Gökçe, Müge, et al.
Publicado: (2015)

Coexistence of myelodysplastic syndrome and acute megakaryoblastic leukemia: An aggressive disease
por: Kasinathan, Ganesh, et al.
Publicado: (2021)

BCR-NTRK2 fusion in a low-grade glioma with distinctive morphology and unexpected aggressive behavior
por: Jones, Karra A., et al.
Publicado: (2019)

DNAJB1-PRKACA fusions occur in oncocytic pancreatic and biliary neoplasms and are not specific for fibrolamellar hepatocellular carcinoma
por: Vyas, Monika, et al.
Publicado: (2019)

Therapy-Related Acute Megakaryoblastic Leukemia in a Lung Cancer Patient
por: Moon, Jung Joo, et al.
Publicado: (2014)

Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis
por: Bernau, Ksenija, et al.
Publicado: (2015)

Clinical Characteristics and Prognosis of 27 Patients with Childhood Acute Megakaryoblastic Leukemia
por: Qi, Haixiao, et al.
Publicado: (2020)

Immunophenotypic Analysis of Acute Megakaryoblastic Leukemia: A EuroFlow Study
por: Brouwer, Nienke, et al.
Publicado: (2022)

Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization
por: Reed, Fiona E., et al.
Publicado: (2022)

Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia With Unusual Immunophenotype
por: Koulmane Laxminarayana, Sindhura Lakshmi, et al.
Publicado: (2023)

Acute Megakaryoblastic Leukemia Developing as Donor Cell Leukemia after Umbilical Cord Blood Transplantation
por: Adachi, Yoshitaka, et al.
Publicado: (2017)

Clinical Courses of Two Pediatric Patients with Acute Megakaryoblastic Leukemia Harboring the CBFA2T3-GLIS2 Fusion Gene
por: Ishibashi, Mayu, et al.
Publicado: (2016)

Acute mono-megakaryoblastic leukemia associated with extreme thrombocytosis and complex karyotype abnormalities
por: Hu, Rong, et al.
Publicado: (2013)

ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia
por: Sun, Xueqin, et al.
Publicado: (2017)

Acute megakaryoblastic blast crisis as a presentation manifestation of chronic myelogenous leukemia
por: Bhattacharya, Jenna B, et al.
Publicado: (2017)

BMP2K dysregulation promotes abnormal megakaryopoiesis in acute megakaryoblastic leukemia
por: Wang, Manman, et al.
Publicado: (2020)

Molecular Mechanisms of the Genetic Predisposition to Acute Megakaryoblastic Leukemia in Infants With Down Syndrome
por: Grimm, Juliane, et al.
Publicado: (2021)

Acute megakaryoblastic leukemia arising in a mediastinal mixed germ cell tumor
por: Alrohaibani, Alaaeddin, et al.
Publicado: (2021)

Discovery of fusion circular RNAs in leukemia with KMT2A::AFF1 rearrangements by the new software CircFusion
por: Dal Molin, Anna, et al.
Publicado: (2022)

Identification of novel, clonally stable, somatic mutations targeting transcription factors PAX5 and NKX2-3, the epigenetic regulator LRIF1, and BRAF in a case of atypical B-cell chronic lymphocytic leukemia harboring a t(14;18)(q32;q21)
por: Burlet, Bénédicte, et al.
Publicado: (2021)

Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome
por: Chebly, Alain, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_itevbncn1b9j6k9bi22jt748rt