Cargando…
A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight?
High-throughput methodologies and machine learning have been central in developing systems-level perspectives in molecular biology. Unfortunately, performing such integrative analyses has traditionally been reserved for bioinformaticians. This is now changing with the appearance of resources to help...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Trends Journals
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318833/ https://www.ncbi.nlm.nih.gov/pubmed/30522862 http://dx.doi.org/10.1016/j.tibs.2018.10.010 |
_version_ | 1783384950999875584 |
---|---|
author | Grabowski, Piotr Rappsilber, Juri |
author_facet | Grabowski, Piotr Rappsilber, Juri |
author_sort | Grabowski, Piotr |
collection | PubMed |
description | High-throughput methodologies and machine learning have been central in developing systems-level perspectives in molecular biology. Unfortunately, performing such integrative analyses has traditionally been reserved for bioinformaticians. This is now changing with the appearance of resources to help bench-side biologists become skilled at computational data analysis and handling large omics data sets. Here, we show an entry route into the field of omics data analytics. We provide information about easily accessible data sources and suggest some first steps for aspiring computational data analysts. Moreover, we highlight how machine learning is transforming the field and how it can help make sense of biological data. Finally, we suggest good starting points for self-learning and hope to convince readers that computational data analysis and programming are not intimidating. |
format | Online Article Text |
id | pubmed-6318833 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier Trends Journals |
record_format | MEDLINE/PubMed |
spelling | pubmed-63188332019-01-10 A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? Grabowski, Piotr Rappsilber, Juri Trends Biochem Sci Article High-throughput methodologies and machine learning have been central in developing systems-level perspectives in molecular biology. Unfortunately, performing such integrative analyses has traditionally been reserved for bioinformaticians. This is now changing with the appearance of resources to help bench-side biologists become skilled at computational data analysis and handling large omics data sets. Here, we show an entry route into the field of omics data analytics. We provide information about easily accessible data sources and suggest some first steps for aspiring computational data analysts. Moreover, we highlight how machine learning is transforming the field and how it can help make sense of biological data. Finally, we suggest good starting points for self-learning and hope to convince readers that computational data analysis and programming are not intimidating. Elsevier Trends Journals 2019-01 /pmc/articles/PMC6318833/ /pubmed/30522862 http://dx.doi.org/10.1016/j.tibs.2018.10.010 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Grabowski, Piotr Rappsilber, Juri A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? |
title | A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? |
title_full | A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? |
title_fullStr | A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? |
title_full_unstemmed | A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? |
title_short | A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? |
title_sort | primer on data analytics in functional genomics: how to move from data to insight? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318833/ https://www.ncbi.nlm.nih.gov/pubmed/30522862 http://dx.doi.org/10.1016/j.tibs.2018.10.010 |
work_keys_str_mv | AT grabowskipiotr aprimerondataanalyticsinfunctionalgenomicshowtomovefromdatatoinsight AT rappsilberjuri aprimerondataanalyticsinfunctionalgenomicshowtomovefromdatatoinsight AT grabowskipiotr primerondataanalyticsinfunctionalgenomicshowtomovefromdatatoinsight AT rappsilberjuri primerondataanalyticsinfunctionalgenomicshowtomovefromdatatoinsight |