Establishment of TP53-knockout canine cells using optimized CRIPSR/Cas9 vector system for canine cancer research

BACKGROUND: Genetic engineering technology such as clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system provides a powerful tool for developing disease models and determining gene functions. Recent interests in canine cancer models have highlighted the necessity of developi...

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Detalles Bibliográficos
Autores principales: Eun, Kiyoung, Park, Min Gi, Jeong, Yeon Woo, Jeong, Yeon Ik, Hyun, Sang-Hwan, Hwang, Woo Suk, Kim, Sung-Hak, Kim, Hyunggee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318917/
https://www.ncbi.nlm.nih.gov/pubmed/30606176
http://dx.doi.org/10.1186/s12896-018-0491-5

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