The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review

AIM: In this retrospective review, we aimed to investigate the long-term efficacy and safety of POEM with follow-up period over 2 years. MATERIALS AND METHODS: A systematic review related to POEM for achalasia was conducted. A literature search was performed in Pubmed, Medline, Ovid, Cochrane and EB...

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Autores principales: Li, Huan, Peng, Wei, Huang, Shu, Ren, Yutang, Peng, Yan, Li, Qing, Wu, Jiao, Fu, Xiangsheng, Tang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318943/
https://www.ncbi.nlm.nih.gov/pubmed/30606216
http://dx.doi.org/10.1186/s13019-018-0811-9
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author Li, Huan
Peng, Wei
Huang, Shu
Ren, Yutang
Peng, Yan
Li, Qing
Wu, Jiao
Fu, Xiangsheng
Tang, Xiaowei
author_facet Li, Huan
Peng, Wei
Huang, Shu
Ren, Yutang
Peng, Yan
Li, Qing
Wu, Jiao
Fu, Xiangsheng
Tang, Xiaowei
author_sort Li, Huan
collection PubMed
description AIM: In this retrospective review, we aimed to investigate the long-term efficacy and safety of POEM with follow-up period over 2 years. MATERIALS AND METHODS: A systematic review related to POEM for achalasia was conducted. A literature search was performed in Pubmed, Medline, Ovid, Cochrane and EBSCO databases on November 2017. The following postoperative outcomes were extracted: Eckardt score, lower esophageal sphincter pressure, complications and clinical success. RESULTS: The total number of patients was 373. The mean operative time was 66.7 min and the overall rate of complications was 21.2%. The mean follow-up period was 30.0 months. The overall clinical success rate was 92.9% and the rate of gastroesophageal reflux disease was 10.2%. Rate of mortality after POEM was 0. CONCLUSIONS: Our study demonstrated that POEM is effective and safe for treating achalasia during the long-term followed up over 2 years.
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spelling pubmed-63189432019-01-08 The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review Li, Huan Peng, Wei Huang, Shu Ren, Yutang Peng, Yan Li, Qing Wu, Jiao Fu, Xiangsheng Tang, Xiaowei J Cardiothorac Surg Review AIM: In this retrospective review, we aimed to investigate the long-term efficacy and safety of POEM with follow-up period over 2 years. MATERIALS AND METHODS: A systematic review related to POEM for achalasia was conducted. A literature search was performed in Pubmed, Medline, Ovid, Cochrane and EBSCO databases on November 2017. The following postoperative outcomes were extracted: Eckardt score, lower esophageal sphincter pressure, complications and clinical success. RESULTS: The total number of patients was 373. The mean operative time was 66.7 min and the overall rate of complications was 21.2%. The mean follow-up period was 30.0 months. The overall clinical success rate was 92.9% and the rate of gastroesophageal reflux disease was 10.2%. Rate of mortality after POEM was 0. CONCLUSIONS: Our study demonstrated that POEM is effective and safe for treating achalasia during the long-term followed up over 2 years. BioMed Central 2019-01-03 /pmc/articles/PMC6318943/ /pubmed/30606216 http://dx.doi.org/10.1186/s13019-018-0811-9 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Li, Huan
Peng, Wei
Huang, Shu
Ren, Yutang
Peng, Yan
Li, Qing
Wu, Jiao
Fu, Xiangsheng
Tang, Xiaowei
The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review
title The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review
title_full The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review
title_fullStr The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review
title_full_unstemmed The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review
title_short The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review
title_sort 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318943/
https://www.ncbi.nlm.nih.gov/pubmed/30606216
http://dx.doi.org/10.1186/s13019-018-0811-9
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