Prevalence of BRCA1 and BRCA2 pathogenic and likely pathogenic variants in non-selected ovarian carcinoma patients in Brazil

BACKGROUND: BRCA1/2 pathogenic (P) and likely pathogenic (LP) germline variants are frequent among patients with ovarian carcinoma. However, these variants have not been extensively characterized in patients with ovarian cancer in Brazil. METHODS: In this retrospective study we evaluated clinical ch...

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Detalles Bibliográficos
Autores principales: Cotrim, Deborah Porto, Ribeiro, Adriana Regina Gonçalves, Paixão, Daniele, de Queiroz Soares, Diogo Cordeiro, Jbili, Rima, Pandolfi, Natasha Carvalho, Cezana, Camila, de Cássia Mauro, Carine, Mantoan, Henrique, Bovolim, Graziele, de Brot, Louise, Torrezan, Giovana Tardin, Carraro, Dirce Maria, Baiocchi, Glauco, da Cruz Formiga, Maria Nirvana, da Costa, Alexandre A. B. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319008/
https://www.ncbi.nlm.nih.gov/pubmed/30606148
http://dx.doi.org/10.1186/s12885-018-5235-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319008/
https://www.ncbi.nlm.nih.gov/pubmed/30606148
http://dx.doi.org/10.1186/s12885-018-5235-3

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