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Chronic Obstructive Pulmonary Disease with Anemia as Comorbidity in North Indian Population

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and mortality worldwide. Anemia is seen as a common comorbidity in COPD patients associated with reduced functional capacity, impaired quality of life, greater likelihood of hospitalization, and early mortal...

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Autores principales: Pandey, Sarika, Garg, Rajiv, Kant, Surya, Gaur, Priyanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319040/
https://www.ncbi.nlm.nih.gov/pubmed/30662881
http://dx.doi.org/10.4103/abr.abr_128_18
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author Pandey, Sarika
Garg, Rajiv
Kant, Surya
Gaur, Priyanka
author_facet Pandey, Sarika
Garg, Rajiv
Kant, Surya
Gaur, Priyanka
author_sort Pandey, Sarika
collection PubMed
description BACKGROUND: Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and mortality worldwide. Anemia is seen as a common comorbidity in COPD patients associated with reduced functional capacity, impaired quality of life, greater likelihood of hospitalization, and early mortality. The aim is to study the prevalence of anemia in patients with COPD and to study its association with different parameters. MATERIALS AND METHODS: In the present case–control study, 150 stable COPD patients were enrolled from the Outpatient Department of Respiratory Medicine, King George Medical University, Lucknow, from October 2015 to January 2017. GraphPad PRISM version 6.01 was used for the analysis of data. Chi-square test was used to compare between the groups. P < 0.05 was considered statistically significant. RESULTS: The present study showed the prevalence of anemia in COPD patients to be 31.6%. The mean hemoglobin level in anemic group was 11.04 ± 1.1 g/dl, whereas in nonanemic group, it was 13.9 ± 0.8 g/dl. Anemia was significantly associated with increased dyspnea in our study which was assessed by modified Medical Research Council grade (P = 0.04). CONCLUSION: The prevalence of anemia in COPD patients was 31.6%. Anemia is present as comorbidity in COPD patients and is associated with poor quality of life and increased morbidity in the form of number of exacerbation and hospital admission. Identification and correction of anemia in COPD patients may improve their clinical outcome.
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spelling pubmed-63190402019-01-18 Chronic Obstructive Pulmonary Disease with Anemia as Comorbidity in North Indian Population Pandey, Sarika Garg, Rajiv Kant, Surya Gaur, Priyanka Adv Biomed Res Original Article BACKGROUND: Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and mortality worldwide. Anemia is seen as a common comorbidity in COPD patients associated with reduced functional capacity, impaired quality of life, greater likelihood of hospitalization, and early mortality. The aim is to study the prevalence of anemia in patients with COPD and to study its association with different parameters. MATERIALS AND METHODS: In the present case–control study, 150 stable COPD patients were enrolled from the Outpatient Department of Respiratory Medicine, King George Medical University, Lucknow, from October 2015 to January 2017. GraphPad PRISM version 6.01 was used for the analysis of data. Chi-square test was used to compare between the groups. P < 0.05 was considered statistically significant. RESULTS: The present study showed the prevalence of anemia in COPD patients to be 31.6%. The mean hemoglobin level in anemic group was 11.04 ± 1.1 g/dl, whereas in nonanemic group, it was 13.9 ± 0.8 g/dl. Anemia was significantly associated with increased dyspnea in our study which was assessed by modified Medical Research Council grade (P = 0.04). CONCLUSION: The prevalence of anemia in COPD patients was 31.6%. Anemia is present as comorbidity in COPD patients and is associated with poor quality of life and increased morbidity in the form of number of exacerbation and hospital admission. Identification and correction of anemia in COPD patients may improve their clinical outcome. Medknow Publications & Media Pvt Ltd 2018-12-19 /pmc/articles/PMC6319040/ /pubmed/30662881 http://dx.doi.org/10.4103/abr.abr_128_18 Text en Copyright: © 2018 Advanced Biomedical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Pandey, Sarika
Garg, Rajiv
Kant, Surya
Gaur, Priyanka
Chronic Obstructive Pulmonary Disease with Anemia as Comorbidity in North Indian Population
title Chronic Obstructive Pulmonary Disease with Anemia as Comorbidity in North Indian Population
title_full Chronic Obstructive Pulmonary Disease with Anemia as Comorbidity in North Indian Population
title_fullStr Chronic Obstructive Pulmonary Disease with Anemia as Comorbidity in North Indian Population
title_full_unstemmed Chronic Obstructive Pulmonary Disease with Anemia as Comorbidity in North Indian Population
title_short Chronic Obstructive Pulmonary Disease with Anemia as Comorbidity in North Indian Population
title_sort chronic obstructive pulmonary disease with anemia as comorbidity in north indian population
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319040/
https://www.ncbi.nlm.nih.gov/pubmed/30662881
http://dx.doi.org/10.4103/abr.abr_128_18
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