Checkpoint inhibitors: What gastroenterologists need to know

Checkpoint inhibitors are increasingly being used in clinical practice. They can cause various gastrointestinal, hepatic and pancreatic side effects. As these side effects can be serious, appropriate management is essential. The different checkpoint inhibitors with their mechanisms of action and ind...

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Autor principal: Ahmed, Monjur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319137/
https://www.ncbi.nlm.nih.gov/pubmed/30622372
http://dx.doi.org/10.3748/wjg.v24.i48.5433
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author Ahmed, Monjur
author_facet Ahmed, Monjur
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description Checkpoint inhibitors are increasingly being used in clinical practice. They can cause various gastrointestinal, hepatic and pancreatic side effects. As these side effects can be serious, appropriate management is essential. The different checkpoint inhibitors with their mechanisms of action and indications, as well as evaluation and management of gastrointestinal, hepatic and pancreatic side effects, are discussed in this article.
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spelling pubmed-63191372019-01-08 Checkpoint inhibitors: What gastroenterologists need to know Ahmed, Monjur World J Gastroenterol Minireviews Checkpoint inhibitors are increasingly being used in clinical practice. They can cause various gastrointestinal, hepatic and pancreatic side effects. As these side effects can be serious, appropriate management is essential. The different checkpoint inhibitors with their mechanisms of action and indications, as well as evaluation and management of gastrointestinal, hepatic and pancreatic side effects, are discussed in this article. Baishideng Publishing Group Inc 2018-12-28 2018-12-28 /pmc/articles/PMC6319137/ /pubmed/30622372 http://dx.doi.org/10.3748/wjg.v24.i48.5433 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Ahmed, Monjur
Checkpoint inhibitors: What gastroenterologists need to know
title Checkpoint inhibitors: What gastroenterologists need to know
title_full Checkpoint inhibitors: What gastroenterologists need to know
title_fullStr Checkpoint inhibitors: What gastroenterologists need to know
title_full_unstemmed Checkpoint inhibitors: What gastroenterologists need to know
title_short Checkpoint inhibitors: What gastroenterologists need to know
title_sort checkpoint inhibitors: what gastroenterologists need to know
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319137/
https://www.ncbi.nlm.nih.gov/pubmed/30622372
http://dx.doi.org/10.3748/wjg.v24.i48.5433
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