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“I6 passages: on the reproduction of a human embryonic stem cell line from Israel to France”

The first French clinical trial using human embryonic stem cells for regenerative purposes was launched in 2014, using the I6 stem cell line that was imported from Israel. From Israel to France, national reproductive policies and practices inform how basic scientists produce, manage and circulate ce...

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Detalles Bibliográficos
Autores principales: Merleau-Ponty, Noémie, Vertommen, Sigrid, Pucéat, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Routledge 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319182/
https://www.ncbi.nlm.nih.gov/pubmed/30679931
http://dx.doi.org/10.1080/14636778.2018.1548269
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author Merleau-Ponty, Noémie
Vertommen, Sigrid
Pucéat, Michel
author_facet Merleau-Ponty, Noémie
Vertommen, Sigrid
Pucéat, Michel
author_sort Merleau-Ponty, Noémie
collection PubMed
description The first French clinical trial using human embryonic stem cells for regenerative purposes was launched in 2014, using the I6 stem cell line that was imported from Israel. From Israel to France, national reproductive policies and practices inform how basic scientists produce, manage and circulate cells across countries. Building on an interdisciplinary co-production involving two social scientists and a life scientist, this article suggests that biobanks passage cells from in vitro fertilization to stem cell science and from country to country by modifying their reproductive meaning. Four passages are described: the absence of cells in 2005 when the research started in France; the presence of supernumerary embryos available for research in Israeli IVF biobanks; the production of the I6 stem cell bank in Israel; the importation and laboratory biobanking of the cells in France. Human embryonic stem cell lines can never be completely disentangled from reproduction.
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spelling pubmed-63191822019-01-22 “I6 passages: on the reproduction of a human embryonic stem cell line from Israel to France” Merleau-Ponty, Noémie Vertommen, Sigrid Pucéat, Michel New Genet Soc Articles The first French clinical trial using human embryonic stem cells for regenerative purposes was launched in 2014, using the I6 stem cell line that was imported from Israel. From Israel to France, national reproductive policies and practices inform how basic scientists produce, manage and circulate cells across countries. Building on an interdisciplinary co-production involving two social scientists and a life scientist, this article suggests that biobanks passage cells from in vitro fertilization to stem cell science and from country to country by modifying their reproductive meaning. Four passages are described: the absence of cells in 2005 when the research started in France; the presence of supernumerary embryos available for research in Israeli IVF biobanks; the production of the I6 stem cell bank in Israel; the importation and laboratory biobanking of the cells in France. Human embryonic stem cell lines can never be completely disentangled from reproduction. Routledge 2018-12-02 /pmc/articles/PMC6319182/ /pubmed/30679931 http://dx.doi.org/10.1080/14636778.2018.1548269 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Merleau-Ponty, Noémie
Vertommen, Sigrid
Pucéat, Michel
“I6 passages: on the reproduction of a human embryonic stem cell line from Israel to France”
title “I6 passages: on the reproduction of a human embryonic stem cell line from Israel to France”
title_full “I6 passages: on the reproduction of a human embryonic stem cell line from Israel to France”
title_fullStr “I6 passages: on the reproduction of a human embryonic stem cell line from Israel to France”
title_full_unstemmed “I6 passages: on the reproduction of a human embryonic stem cell line from Israel to France”
title_short “I6 passages: on the reproduction of a human embryonic stem cell line from Israel to France”
title_sort “i6 passages: on the reproduction of a human embryonic stem cell line from israel to france”
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319182/
https://www.ncbi.nlm.nih.gov/pubmed/30679931
http://dx.doi.org/10.1080/14636778.2018.1548269
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