Preclinical Evaluation of ADVM-022, a Novel Gene Therapy Approach to Treating Wet Age-Related Macular Degeneration

Inhibition of vascular endothelial growth factor, a key contributor to the choroidal neovascularization associated with wet age-related macular degeneration, is the mode of action of several approved therapies, including aflibercept, which requires frequent intravitreal injections to provide clinica...

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Detalles Bibliográficos
Autores principales: Grishanin, Ruslan, Vuillemenot, Brian, Sharma, Pallavi, Keravala, Annahita, Greengard, Judith, Gelfman, Claire, Blumenkrantz, Mark, Lawrence, Matthew, Hu, Wenzheng, Kiss, Szilárd, Gasmi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319194/
https://www.ncbi.nlm.nih.gov/pubmed/30528929
http://dx.doi.org/10.1016/j.ymthe.2018.11.003

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