Metformin alters H2A.Z dynamics and regulates androgen dependent prostate cancer progression

Epigenetic mechanisms involved in prostate cancer include hypermethylation of tumor suppressor genes, general hypomethylation of the genome, and alterations in histone posttranslational modifications (PTMs). In addition, over expression of the histone variant H2A.Z as well as deregulated expression...

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Detalles Bibliográficos
Autores principales: Tyagi, Monica, Cheema, Manjinder S., Dryhurst, Deanna, Eskiw, Christopher H., Ausió, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319340/
https://www.ncbi.nlm.nih.gov/pubmed/30651935
http://dx.doi.org/10.18632/oncotarget.26457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319340/
https://www.ncbi.nlm.nih.gov/pubmed/30651935
http://dx.doi.org/10.18632/oncotarget.26457

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