Elevated histone H3 acetylation is associated with genes involved in T lymphocyte activation and glutamate decarboxylase antibody production in patients with type 1 diabetes

AIMS/INTRODUCTION: Genetic and epigenetic mechanisms have been implicated in the pathogenesis of type 1 diabetes, and histone acetylation is an epigenetic modification pattern that activates gene transcription. However, the genome‐wide histone H3 acetylation in new‐onset type 1 diabetes patients has...

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Detalles Bibliográficos
Autores principales: Wang, Yanfei, Hou, Can, Wisler, Jonathan, Singh, Kanhaiya, Wu, Chao, Xie, Zhiguo, Lu, Qianjin, Zhou, Zhiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319479/
https://www.ncbi.nlm.nih.gov/pubmed/29791073
http://dx.doi.org/10.1111/jdi.12867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319479/
https://www.ncbi.nlm.nih.gov/pubmed/29791073
http://dx.doi.org/10.1111/jdi.12867

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