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Anti-neuroinflammatory Effects of 12-Dehydrogingerdione in LPS-Activated Microglia through Inhibiting Akt/IKK/NF-κB Pathway and Activating Nrf-2/HO-1 Pathway

Ginger, one of worldwide consumed dietary spice, is not only famous as food supplements, but also believed to exert a variety of remarkable pharmacological activity as herbal remedies. In this study, a ginger constituent, 12-dehydrogingerdione (DHGD) was proven that has comparable anti-inflammatory...

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Detalles Bibliográficos
Autores principales: Zhao, Dong, Gu, Ming-Yao, Xu, Jiu Liang, Zhang, Li Jun, Ryu, Shi Yong, Yang, Hyun Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319549/
https://www.ncbi.nlm.nih.gov/pubmed/30404129
http://dx.doi.org/10.4062/biomolther.2018.104