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EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis

The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protein of 115 amino acids, is essential for mediating E...

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Detalles Bibliográficos
Autores principales:	Sala, Claudia, Odermatt, Nina T., Soler-Arnedo, Paloma, Gülen, Muhammet F., von Schultz, Sofia, Benjak, Andrej, Cole, Stewart T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319747/ https://www.ncbi.nlm.nih.gov/pubmed/30571761 http://dx.doi.org/10.1371/journal.ppat.1007491

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