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Determinants of drug-target interactions at the single cell level

The physiochemical determinants of drug-target interactions in the microenvironment of the cell are complex and generally not defined by simple diffusion and intrinsic chemical reactivity. Non-specific interactions of drugs and macromolecules in cells are rarely considered formally in assessing phar...

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Detalles Bibliográficos
Autores principales:	Elgart, Vlad, Lin, Jia-Ren, Loscalzo, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319770/ https://www.ncbi.nlm.nih.gov/pubmed/30571695 http://dx.doi.org/10.1371/journal.pcbi.1006601

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