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CD8(+) T cells modulate autosomal dominant polycystic kidney disease progression
Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent inherited nephropathy. To date, therapies alleviating the disease have largely focused on targeting abnormalities in renal epithelial cell signaling. ADPKD has many hallmarks of cancer, where targeting T cells has brought nov...
Autores principales: | Kleczko, Emily K., Marsh, Kenneth H., Tyler, Logan C., Furgeson, Seth B., Bullock, Bonnie L., Altmann, Christopher J., Miyazaki, Makoto, Gitomer, Berenice Y., Harris, Peter C., Weiser-Evans, Mary C.M., Chonchol, Michel B., Clambey, Eric T., Nemenoff, Raphael A., Hopp, Katharina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319903/ https://www.ncbi.nlm.nih.gov/pubmed/30249452 http://dx.doi.org/10.1016/j.kint.2018.06.025 |
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