Cargando…

A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement

A recurrent theme in viral immune evasion is the sabotage of MHC-I antigen presentation, which brings virus the concomitant issue of ‘missing-self’ recognition by NK cells that use inhibitory receptors to detect surface MHC-I proteins. Here, we report that rodent herpesvirus Peru (RHVP) encodes a Qa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xiaoli, Piersma, Sytse J, Nelson, Christopher A, Dai, Ya-Nan, Christensen, Ted, Lazear, Eric, Yang, Liping, Sluijter, Marjolein, van Hall, Thorbald, Hansen, Ted H, Yokoyama, Wayne M, Fremont, Daved H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320069/ https://www.ncbi.nlm.nih.gov/pubmed/30575523 http://dx.doi.org/10.7554/eLife.38667

Ejemplares similares

Recognition of the Class Ib Molecule Qa-1(b) by Putative Activating Receptors Cd94/Nkg2c and Cd94/Nkg2e on Mouse Natural Killer Cells
por: Vance, Russell E., et al.
Publicado: (1999)

The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function
por: Li, Shasha, et al.
Publicado: (2022)

Analysis of Qa-1(b)Peptide Binding Specificity and the Capacity of Cd94/Nkg2a to Discriminate between Qa-1–Peptide Complexes
por: Kraft, Jennifer R., et al.
Publicado: (2000)

Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING
por: Piersma, Sytse J, et al.
Publicado: (2020)

Mouse CD94/NKG2A Is a Natural Killer Cell Receptor for the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule Qa-1(b)
por: Vance, Russell E., et al.
Publicado: (1998)

Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy
por: Ghasemi, Reza, et al.
Publicado: (2016)

HIF1α is required for NK cell metabolic adaptation during virus infection
por: Victorino, Francisco, et al.
Publicado: (2021)

T Cells Engaging the Conserved MHC Class Ib Molecule Qa-1(b) with TAP-Independent Peptides Are Semi-Invariant Lymphocytes
por: Doorduijn, Elien M., et al.
Publicado: (2018)

The nonpolymorphic MHC Qa-1(b) mediates CD8(+) T cell surveillance of antigen-processing defects
por: Oliveira, Cláudia C., et al.
Publicado: (2010)

The nonpolymorphic MHC Qa-1(b) mediates CD8(+) T cell surveillance of antigen-processing defects
por: Oliveira, Cláudia C., et al.
Publicado: (2010)

NKG2A Complexed with CD94 Defines a Novel Inhibitory Natural Killer Cell Receptor
por: Brooks, Andrew G., et al.
Publicado: (1997)

Structural Mechanism of ER Retrieval of MHC Class I by Cowpox
por: McCoy, William H., et al.
Publicado: (2012)

The nonclassical MHC class I Qa-1 expressed in layer 6 neurons regulates activity-dependent plasticity via microglial CD94/NKG2 in the cortex
por: Marin, Ioana A., et al.
Publicado: (2022)

Adrenal malakoplakia a rare lesion that mimics a neoplasm
por: Rodríguez González, Orión Erenhú, et al.
Publicado: (2023)

Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR(+)NKG2A(-) NK cells
por: Bennstein, Sabrina Bianca, et al.
Publicado: (2020)

The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses
por: Serrero, Manutea C, et al.
Publicado: (2022)

mTORC1 and mTORC2 differentially promote natural killer cell development
por: Yang, Chao, et al.
Publicado: (2018)

Engineered natural killer cells impede the immunometabolic CD73-adenosine axis in solid tumors
por: Chambers, Andrea M, et al.
Publicado: (2022)

Natural killer (NK) cell-derived extracellular-vesicle shuttled microRNAs control T cell responses
por: Dosil, Sara G, et al.
Publicado: (2022)

NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division
por: Borst, Linda, et al.
Publicado: (2021)

Targeting of IL-2 to cytotoxic lymphocytes as an improved method of cytokine-driven immunotherapy
por: Lazear, Eric, et al.
Publicado: (2017)

Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion
por: Marotel, Marie, et al.
Publicado: (2021)

High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors
por: Marçais, Antoine, et al.
Publicado: (2017)

Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells
por: Kasler, Herbert G, et al.
Publicado: (2018)

Control of Viral Infection by Natural Killer Cell Inhibitory Receptors
por: Parikh, Bijal A., et al.
Publicado: (2020)

Liver type 1 innate lymphoid cells lacking IL-7 receptor are a native killer cell subset fostered by parenchymal niches
por: Asahi, Takuma, et al.
Publicado: (2023)

Deciphering the biology of NKG2C+ natural killer cells
por: Rölle, Alexander
Publicado: (2015)

Development and Function of CD94-Deficient Natural Killer Cells
por: Orr, Mark T., et al.
Publicado: (2010)

Monalizumab: inhibiting the novel immune checkpoint NKG2A
por: van Hall, Thorbald, et al.
Publicado: (2019)

Natural killer cells in herpesvirus infections
por: Münz, Christian, et al.
Publicado: (2017)

Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis
por: Ghoshal, Pushpankur, et al.
Publicado: (2019)

Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4(+) and CD8(+) T-lymphocytes
por: Moshfegh, C.M., et al.
Publicado: (2019)

Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
por: Godo, Shigeo, et al.
Publicado: (2021)

Anti-inflammatory Treatment and Cardiovascular Outcomes: Results of Clinical Trials
por: Lorenzatti, Alberto J
Publicado: (2021)

Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis: Impact of Inflammation and Antirheumatic Treatment
por: Kerola, Anne Mirjam, et al.
Publicado: (2021)

The Role of C-reactive Protein in Patient Risk Stratification and Treatment
por: Arroyo-Espliguero, Ramón, et al.
Publicado: (2021)

Inflammation and Cardiovascular Disease: The Future
por: Arnold, Natalie, et al.
Publicado: (2021)

Small bowel stomas are associated with higher risk of circulating food-specific-IgG than patients with organic gastrointestinal conditions and colostomies
por: Carson, Walker K, et al.
Publicado: (2022)

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells
por: Davis, Zachary B., et al.
Publicado: (2016)

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis
por: Borrego, Francisco, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_67d451n4840jjclc7p2jkm8j8j