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Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations

BACKGROUND: The innate immune system senses viral infection through pattern recognition receptors (PRRs), leading to type I interferon production. The role of type I interferon and PPRs in rhinovirus-induced asthma exacerbations in vivo are uncertain. OBJECTIVES: We sought to compare bronchial mucos...

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Detalles Bibliográficos
Autores principales:	Zhu, Jie, Message, Simon D., Mallia, Patrick, Kebadze, Tatiana, Contoli, Marco, Ward, Christine K., Barnathan, Elliot S., Mascelli, Mary Ann, Kon, Onn M., Papi, Alberto, Stanciu, Luminita A., Edwards, Michael R., Jeffery, Peter K., Johnston, Sebastian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mosby 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320262/ https://www.ncbi.nlm.nih.gov/pubmed/29698627 http://dx.doi.org/10.1016/j.jaci.2018.04.003

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